1)
This is the Copper Coronet, one of the most important areas of the game. You'll be able to recruit Anomen, Nalia, and Korgan from inside here, as well as obtain numerous quests. You can even obtain a quest just outside the Copper Coronet if you have Mazzy in your party. You'll meet an ogre who harasses and challenges Mazzy just because she's a halfing. Mazzy will accept a duel. Now, just enter the tavern and you'll meet an alchemist near the stairs. The alchemist will offer you a potion to drug the ogre. You can accept it or refuse it, but I do recommend it since Mazzy will be fighting without her equipment. If you do accept it, find the ogre's lover and convince her to mix the potion in the ogre's drink. I don't know if this option will affect Mazzy's knighthood, but I had not seen any negative side effects.

2)
This is the enterance to the Planar Sphere. To open the Sphere, you need Valygar (the NPC from the Umar Hills) or his corpse. If your main character is a mage, you will gain the sphere as your stronhold once you've defeated Lavok.

3)
The location of the final confrontation in the Korgan Quest. You'll get the Book of Kaza from the leader of this ragtag bunch, which can be sold to various shops.

4)
Here you'll find the Slaver Compound, which can be entered in one of two ways. One way is through the front door (although I had a bit of a scuffle with the guard and was locked out), or you can travel through the sewers beneath the Copper Coronet and up through a doorway inside the compound.

5)
This is Gaelan Bayle's home, the man who offers to help you find Imoen near the beginning of the game. Additionally, on the second floor of his home is a thief selling some pretty decent wares. Make sure to pay him a visit.

6)
Another derelict home resides here. If you have Jaheira in your party when exploring the Docks District, you may have been cursed by a Baron. If so, here is where you'll want to travel in order to end his life, thus ending the curse.

7)
You can find a Temple of Ilmater perched upon an upper level here. There is one thing definitely worthy of mention here. After you have finished the Asylum, you can bring Yoshimo's heart back here (after you've killed him) for a whopping 200,000 experience!